Semi Solids and Liquids
What are Semi Solids and Liquids in a pharmaceutical manufacturing context?
Semi Solids and Liquids Definition | There are a large range of semi-solid and liquid formulation techniques employed in pharmaceutical manufacturing. Self-emulsifying pharmaceutical formulations are used to improve the oral bioavailability of poorly soluble drugs, typically increasing Cmax and decreasing Tmax concentrations. These formulations consist of a surfactant, lipid and cosolvent in varying concentrations which form a microemulsion in the presence of water. They are typically presented in gelatin capsules. These formulations are commonly known as Self Emulsifying Drug Delivery Systems (SEDDS). Simple liquid formulations consist of a drug in solution presented in a capsule. The solvent is determined by the chemistry and required concentration of the drug. Precipitation of the drug can be triggered by the dilution of the capsule at specific pH ranges.
Semi Solids and Liquids White Papers
Formulation and In Vitro Characterization of Solid Self Emulsifying Drug Delivery System of Ramipril Prepared by Adsorption Technique
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Semi Solids and Liquids Articles
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